Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14074153 | 0.94 | HCRTR2 (0.30) | HCRTR2 | |
| SCHEMBL21537525 | 0.91 | CTSL (0.35) | HCRTR2JAK2JAK1CTSLCTSB | |
| SCHEMBL2668604 | 0.91 | CTSL (0.35) | HCRTR2JAK2JAK1CTSLCTSB | |
| SCHEMBL8263000 | 0.91 | CTSL (0.35) | HCRTR2JAK2JAK1CTSLCTSB | |
| SCHEMBL803142 | 0.85 | HCRTR2 (0.33) | HCRTR2JAK2JAK1CTSLCTSB | |
| SCHEMBL20664323 | 0.85 | HCRTR2 (0.33) | HCRTR2JAK2JAK1CTSLCTSB | |
| SCHEMBL11957389 | 0.85 | HCRTR2 (0.33) | HCRTR2JAK2JAK1CTSLCTSB | |
| SCHEMBL14701093 | 0.85 | HCRTR2 (0.33) | HCRTR2JAK2JAK1CTSLCTSB | |
| SCHEMBL20664270 | 0.80 | DAO (0.33) | DAO | |
| SCHEMBL13038169 | 0.80 | DAO (0.40) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607451-B1 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2019-01-23 | — | — | EP | disclosed |