Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.68 |
| ▸ | FLT3 | P36888 | 4/20 | 0.63 |
| ▸ | MAOB | P27338 | 7/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.57 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19303535 | 0.83 | FLT3 (0.69) | ALDH1A1MEN1KMT2AABCB1FLT3 | |
| Tetramethylscutellarein SCHEMBL739115 | 0.82 | MEN1 (1.00) | ALDH1A1MEN1KMT2AABCB1FLT3 | |
| Trimethylapigenin SCHEMBL1421585 | 0.81 | ABCB1 (1.00) | ALDH1A1MEN1KMT2AABCB1FLT3 | |
| Trimethylapigenin SCHEMBL29350875 | 0.81 | ABCB1 (1.00) | ALDH1A1MEN1KMT2AABCB1FLT3 | |
| Ladanein SCHEMBL737069 | 0.80 | FLT3 (0.81) | ALDH1A1MEN1KMT2AABCB1FLT3 | |
| SCHEMBL1976673 | 0.79 | MEN1 (0.79) | ALDH1A1MEN1KMT2AABCB1FLT3 | |
| SCHEMBL6932015 | 0.79 | MEN1 (0.79) | ALDH1A1MEN1KMT2AABCB1FLT3 | |
| SCHEMBL10031424 | 0.79 | FLT3 (0.84) | ALDH1A1MEN1KMT2AABCB1FLT3 | |
| SCHEMBL20100895 | 0.78 | ABCB1 (0.82) | ALDH1A1MEN1KMT2AABCB1FLT3 | |
| SCHEMBL3825575 | 0.78 | AR (0.80) | ALDH1A1MEN1KMT2AABCB1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2828248-B1 | FLAVONE DERIVATIVES AND THEIR USE | TWINCORE GMBH (DE) | 2019-01-23 | — | — | EP | disclosed |