Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 6/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 4/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | KIT | P10721 | 1/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.69 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.69 |
| ▸ | RELA | Q04206 | 1/20 | 0.69 |
| ▸ | MAOB | P27338 | 3/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242511 | 0.86 | KMT2A (0.81) | FLT3KMT2AMAPTMEN1NPC1 | |
| SCHEMBL28732976 | 0.84 | FLT3 (0.81) | FLT3KMT2AMAPTMEN1NPC1 | |
| SCHEMBL29504103 | 0.84 | FLT3 (0.81) | FLT3KMT2AMAPTMEN1NPC1 | |
| SCHEMBL20664416 | 0.83 | ALDH1A1 (0.69) | FLT3KMT2AMAPTMEN1NPC1 | |
| Pectolinarigenin SCHEMBL29606971 | 0.81 | MAPT (1.00) | FLT3KMT2AMAPTMEN1NPC1 | |
| Pectolinarigenin SCHEMBL243686 | 0.81 | MAPT (1.00) | FLT3KMT2AMAPTMEN1NPC1 | |
| Apigenin Dimethylether SCHEMBL29392759 | 0.81 | MAOB (1.00) | FLT3KMT2AMAPTMEN1NPC1 | |
| Apigenin Dimethylether SCHEMBL1176691 | 0.81 | MAOB (1.00) | FLT3KMT2AMAPTMEN1NPC1 | |
| SCHEMBL8063178 | 0.80 | FLT3 (0.83) | FLT3KMT2AMAPTMEN1NPC1 | |
| SCHEMBL28592818 | 0.80 | MAPT (0.74) | FLT3KMT2AMAPTMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017146332-A1 | NOVEL USE OF CHROMONE DERIVATIVE AS PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING FIBROSIS BY USING EPITHELIAL-MESENCHYMAL TRANSITION INHIBITORY ACTIVITY THEREOF | (주)오스티오뉴로젠 | 2017-08-31 | — | — | WO | disclosed |