SCHEMBL2066640

SCHEMBL2066640

CCc1ccc2ncc(S(N)(=O)=O)n2n1

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TNF P01375 14/20 0.61
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
TGFBR1 P36897 1/20 0.34
FYN P06241 4/20 0.34
GRK5 P34947 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2064906 0.88 TNF (0.58) TNFCA2TGFBR1FYNGRK5
SCHEMBL2066977 0.86 TNF (0.56) TNFCA12CA1CA2CA9
SCHEMBL2068600 0.85 TNF (0.47) TNFFYN
SCHEMBL2065978 0.80 TNF (0.67) TNFCA12CA1CA2CA9
SCHEMBL2066936 0.78 TNF (0.57) TNFTGFBR1
SCHEMBL2067972 0.76 TNF (0.61) TNFTGFBR1
SCHEMBL2065995 0.76 TNF (0.61) TNFCA1CA2FYN
SCHEMBL13080171 0.74 FYN (0.37) FYNGRK5
SCHEMBL2066212 0.74 TNF (0.44) TNFFYN
SCHEMBL21756366 0.73 TGFBR1 (0.50) TGFBR1FYNGRK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148524-B2 Process for producing sulfonyl chloride compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-03 US disclosed
EP-1932846-B1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2010-10-27 EP disclosed
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-01 US disclosed
EP-1932846-A1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SALL4, CLCN2, CLIC1 TNF 4785/4885CA12 1529/4885CA1 1402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.