SCHEMBL2067972

SCHEMBL2067972

CC(C)c1ccc2ncc(S(N)(=O)=O)n2n1

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TNF P01375 11/20 0.61
CHRNA7 P36544 3/20 0.36
APLNR P35414 1/20 0.35
TGFBR1 P36897 2/20 0.34
KCNH2 Q12809 1/20 0.31
LOXL2 Q9Y4K0 1/20 0.31
DGAT1 O75907 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2065119 0.85 TNF (0.47) TNFAPLNRTGFBR1KCNH2
SCHEMBL2065978 0.80 TNF (0.67) TNFTGFBR1KCNH2
SCHEMBL2066640 0.76 TNF (0.61) TNFTGFBR1
SCHEMBL2065995 0.76 TNF (0.61) TNF
SCHEMBL16017507 0.74 TGFBR1 (0.33) TGFBR1DGAT1
SCHEMBL17132525 0.74 PIK3CD (0.33) TGFBR1DGAT1
SCHEMBL2064906 0.74 TNF (0.58) TNFTGFBR1
SCHEMBL20625676 0.73 TGFBR1 (0.56) TGFBR1
SCHEMBL2066936 0.72 TNF (0.57) TNFTGFBR1
SCHEMBL2066401 0.72 ALDH1A1 (0.32) TNFCHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148524-B2 Process for producing sulfonyl chloride compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-03 US disclosed
EP-1932846-B1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2010-10-27 EP disclosed
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-01 US disclosed
EP-1932846-A1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SALL4, CLCN2, CLIC1 TNF 4785/4885CHRNA7 3361/4885APLNR 4557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.