SCHEMBL947512

SCHEMBL947512

Clc1ccccc1C(Cl)Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.50
HIF1A Q16665 3/20 0.50
LMNA P02545 2/20 0.50
CYP2C19 P33261 2/20 0.50
CYP2C9 P11712 1/20 0.50
KDM4E B2RXH2 1/20 0.50
NR1I2 O75469 1/20 0.50
ABCB11 O95342 1/20 0.50
NR3C1 P04150 1/20 0.50
PGR P06401 1/20 0.50
CYP3A4 P08684 1/20 0.50
ADRA2A P08913 1/20 0.50
ADORA3 P0DMS8 1/20 0.50
MAPT P10636 1/20 0.50
CNR1 P21554 1/20 0.50
SLC6A2 P23975 1/20 0.50
ACAT1 P24752 1/20 0.50
MAPK1 P28482 1/20 0.50
SLC6A4 P31645 1/20 0.50
HTR2B P41595 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30848757 1.00 TSHR (0.50) TSHRHIF1ALMNACYP2C19CYP2C9
Chlorobenzene SCHEMBL8128344 0.90 TSHR (0.53) TSHRHIF1ALMNACYP2C19CYP2C9
SCHEMBL11617245 0.82 TSHR (0.50) TSHRHIF1ALMNACYP2C19CYP2C9
SCHEMBL3785333 0.81 TSHR (0.50) TSHRHIF1ALMNACYP2C19CYP2C9
SCHEMBL7646187 0.79 CYP2A6 (0.46) TSHRHIF1ALMNACYP2C19CYP2C9
SCHEMBL2066643 0.79 TSHR (0.53) TSHRHIF1ALMNACYP2C19CYP2C9
SCHEMBL4167758 0.78 TSHR (0.47) TSHRHIF1ALMNACYP2C19CYP2C9
SCHEMBL9130061 0.78 TSHR (0.69) TSHRHIF1ALMNACYP2C19CYP2C9
SCHEMBL1872442 0.78 CYP1A2 (0.58) TSHRHIF1ALMNACYP2C19CYP2C9
SCHEMBL13145152 0.78 ADRB2 (0.47) TSHRHIF1ALMNACYP2C19CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 411 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080553-A High-temperature-resistant sealing rubber material and preparation method thereof 2026-05-26 CN claimed
CN-122017056-A HPLC quantitative detection method for o-methylbenzyl chloride and impurities thereof 山东新华制药股份有限公司 2026-05-12 CN claimed
CN-114904577-B Asymmetric catalyst of chiral porous crosslinked oligopeptide polymer and preparation method thereof 哈尔滨工程大学 2024-10-25 CN claimed
CN-117504735-A Equipment and method for co-producing acyl chloride from o-chlorobenzaldehyde 常州新东化工发展有限公司 2024-02-06 CN claimed
CN-113105302-B Method for co-production of o-chlorobenzyl chloride, o-chlorobenzyl dichloride and o-chlorobenzyl trichloride through o-chlorotoluene chlorination 老河口华辰化学有限公司 2024-01-12 CN claimed
CN-117304007-A Supermolecule macrocyclic arene constructed based on naphthalene ring and biphenyl, and synthetic method and application thereof 西北师范大学 2023-12-29 CN claimed
CN-113233954-B Method for improving selectivity of chlorination reaction process 新乡瑞诚科技股份有限公司 2023-07-07 CN claimed
CN-113856486-B Charged composite nanofiltration membrane based on organic-inorganic nano particles and preparation method thereof 浙江大学 2023-05-23 CN claimed
US-20210323944-A1 IVOSIDENIB FORMS AND PHARMACEUTICAL COMPOSITIONS AGIOS PHARMACEUTICALS, INC. (US) 2021-10-21 US claimed
CN-113105302-A Method for co-production of o-chlorobenzyl chloride, o-dichlorobenzyl chloride and o-chlorotrifluorobenzyl chloride by chlorination of o-chlorotoluene 老河口华辰化学有限公司 2021-07-13 CN claimed
CN-101641326-B Continuous process for the preparation of acyl peroxides UNITED INITIATORS GMBH & CO KG 2013-08-14 CN claimed
CN-102089374-B Preparation for initiating radical reactions UNITED INITIATORS GMBH & CO KG 2013-06-26 CN claimed
CN-101691339-B Compound containing cyclonene and oxime ester structures and preparation method thereof NINGBO INST TECH ZHEJIANG UNIV 2013-04-10 CN claimed
CN-102089374-A Preparation for initiating radical reactions UNITED INITIATORS GMBH & CO KG 2011-06-08 CN claimed
CN-101691339-A Compound containing cyclonene and oxime ester structures and preparation method thereof NINGBO INST TECH ZHEJIANG UNIV 2010-04-07 CN claimed
CN-101641326-A Continuous process for the preparation of acyl peroxides EVONIK DEGUSSA GMBH DE 2010-02-03 CN claimed
CN-101631772-A Method for producing acyl peroxides UNITED INITIATORS GMBH & CO KG 2010-01-20 CN claimed
CN-101070295-A Process for combined production of substituted benzenesulfonyl chloride and substituted benzoyl chloride JIANGSU QINGSHENG CHEMICAL CO (CN) 2007-11-14 CN claimed
CN-1307154-C Photochemical synthesis of vitamin D2Method (2) CHINESE ACAD TECH INST PHYSICS (CN) 2007-03-28 CN claimed
US-5565602-A REACTING A HYDROCARBYL CHLORIDE WITH A CARBONYL SULFIDE AND AMINE IN PRESENCE OF A BASIC CATALYST PHILLIPS PETROLEUM COMPANY (US) 1996-10-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210323944-A1 IVOSIDENIB FORMS AND PHARMACEUTICAL COMPOSITIONS HLA-B, ACVR2B, KPNB1 TSHR 3770/4885HIF1A 2267/4885LMNA 183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.