SCHEMBL20669161

SCHEMBL20669161

CC(=O)N1CC2(CCN(C(=O)[C@H](N)CCCCNC(=O)OC(C)(C)C)CC2)C1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.41
KMT2A Q03164 7/20 0.41
GAA P10253 1/20 0.41
TDP1 Q9NUW8 3/20 0.40
POLB P06746 2/20 0.40
MAPT P10636 1/20 0.40
DPP8 Q6V1X1 3/20 0.39
DPP9 Q86TI2 2/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
DRD2 P14416 4/20 0.38
DPP7 Q9UHL4 2/20 0.38
DPP4 P27487 1/20 0.38
NPSR1 Q6W5P4 2/20 0.38
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22030254 0.90 MEN1 (0.40) MEN1KMT2AGAATDP1POLB
SCHEMBL25597459 0.88 MEN1 (0.41) MEN1KMT2AGAATDP1POLB
SCHEMBL20669172 0.88 MEN1 (0.39) MEN1KMT2AGAATDP1POLB
SCHEMBL21219295 0.81 MEN1 (0.43) MEN1KMT2AGAATDP1POLB
SCHEMBL21219293 0.81 MEN1 (0.43) MEN1KMT2AGAATDP1POLB
SCHEMBL22026260 0.81 HRH3 (0.43) MEN1KMT2AGAATDP1POLB
SCHEMBL20669340 0.81 PAX8 (0.49) MEN1KMT2ATDP1POLBMAPT
SCHEMBL21009797 0.80 MEN1 (0.40) MEN1KMT2AGAATDP1POLB
SCHEMBL19708418 0.80 MEN1 (0.40) MEN1KMT2AGAATDP1POLB
SCHEMBL19707910 0.80 MEN1 (0.46) MEN1KMT2AGAATDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230174487-A1 PHENYLPROPIONAMIDE COMPOUND AND USE THEREOF MEDSHINE DISCOVERY INC. (CN) 2023-06-08 US disclosed
US-20230174487-A1 PHENYLPROPIONAMIDE COMPOUND AND USE THEREOF MEDSHINE DISCOVERY INC. (CN) 2023-06-08 US disclosed
WO-2019015644-A1 PEPTIDE AMIDE COMPOUND AND PREPARATION METHOD AND MEDICAL USE THEREOF 四川海思科制药有限公司 2019-01-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230174487-A1 PHENYLPROPIONAMIDE COMPOUND AND USE THEREOF PAH, TRPV1, TRPA1 MEN1 4181/4885KMT2A 1834/4885GAA 803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.