SCHEMBL21219293

SCHEMBL21219293

CC(C)(C)OC(=O)NCCCC[C@@H](N)C(=O)N1CCC(NC(=O)OC(C)(C)C)(C(=O)O)CC1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.43
KMT2A Q03164 6/20 0.43
GAA P10253 1/20 0.43
DPP8 Q6V1X1 3/20 0.40
DPP7 Q9UHL4 2/20 0.40
DPP9 Q86TI2 2/20 0.40
DPP4 P27487 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
DRD2 P14416 4/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ITGB3 P05106 2/20 0.36
ITGA2B P08514 2/20 0.36
NPC1L1 Q9UHC9 1/20 0.36
FPR3 P25089 1/20 0.36
FPR2 P25090 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21219295 1.00 MEN1 (0.43) MEN1KMT2AGAADPP8DPP7
SCHEMBL21009797 0.91 MEN1 (0.40) MEN1KMT2AGAADPP8DPP7
SCHEMBL19708418 0.91 MEN1 (0.40) MEN1KMT2AGAADPP8DPP7
SCHEMBL20873003 0.88 DPP8 (0.58) DPP8DPP7DPP9DPP4MAPT
SCHEMBL22962171 0.87 MEN1 (0.39) MEN1KMT2AGAADPP8DPP7
SCHEMBL28270789 0.84 MEN1 (0.39) MEN1KMT2AGAADPP8DPP7
SCHEMBL19708141 0.81 DPP8 (0.57) DPP8DPP7DPP9DPP4MAPT
SCHEMBL19708142 0.81 DPP8 (0.57) DPP8DPP7DPP9DPP4MAPT
SCHEMBL20669161 0.81 MEN1 (0.41) MEN1KMT2AGAADPP8DPP7
SCHEMBL21009950 0.81 DPP8 (0.56) DPP8DPP7DPP9DPP4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3521301-B1 POLYAMIDE COMPOUND AND USE THEREOF SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD (CN) 2024-03-06 EP disclosed
US-11084847-B2 Polyamide compound and use thereof SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2021-08-10 US disclosed
US-20200109166-A1 POLYAMIDE COMPOUND AND USE THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2020-04-09 US disclosed
EP-3521301-A1 POLYAMIDE COMPOUND AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2019-08-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11084847-B2 Polyamide compound and use thereof OPRK1, OPRM1, OPRD1 MEN1 4801/4885KMT2A 464/4885GAA 1122/4885
US-20200109166-A1 POLYAMIDE COMPOUND AND USE THEREOF OPRK1, OPRM1, OPRD1 MEN1 4801/4885KMT2A 464/4885GAA 1122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.