SCHEMBL20669262

SCHEMBL20669262

CC(C)CC(C=O)NC(=O)CNC(=O)C(N)Cc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 13/20 0.54
OPRM1 P35372 7/20 0.53
OPRK1 P41145 3/20 0.53
CTSB P07858 1/20 0.49
LTA4H P09960 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22028219 1.00 OPRD1 (0.54) OPRD1OPRM1OPRK1CTSBLTA4H
SCHEMBL22030225 1.00 OPRD1 (0.54) OPRD1OPRM1OPRK1CTSBLTA4H
SCHEMBL22030230 1.00 OPRD1 (0.54) OPRD1OPRM1OPRK1CTSBLTA4H
SCHEMBL29362263 0.93 OPRD1 (0.54) OPRD1OPRM1OPRK1CTSB
SCHEMBL26429187 0.90 OPRD1 (0.55) OPRD1OPRM1OPRK1
SCHEMBL23463561 0.88 CTSB (0.58) CTSBLTA4H
SCHEMBL14242857 0.86 OPRD1 (0.56) OPRD1OPRM1OPRK1CTSB
SCHEMBL24115124 0.85 OPRD1 (0.56) OPRD1OPRM1OPRK1LTA4H
SCHEMBL22028176 0.85 OPRD1 (0.56) OPRD1OPRM1OPRK1LTA4H
SCHEMBL29359869 0.85 OPRD1 (0.57) OPRD1OPRM1OPRK1CTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3656782-B1 PEPTIDE AMIDE COMPOUND AND PREPARATION METHOD AND MEDICAL USE THEREOF SICHUAN HAISCO PHARMACEUTICAL CO LTD (CN) 2021-12-22 EP disclosed
EP-3656782-A1 PEPTIDE AMIDE COMPOUND AND PREPARATION METHOD AND MEDICAL USE THEREOF Sichuan Haisco Pharmaceutical Co., Ltd. (CN) 2020-05-27 EP disclosed
WO-2019015644-A1 PEPTIDE AMIDE COMPOUND AND PREPARATION METHOD AND MEDICAL USE THEREOF 四川海思科制药有限公司 2019-01-24 WO disclosed