SCHEMBL24115124

SCHEMBL24115124

CC(C)CC(C)NC(=O)CNC(=O)[C@H](N)Cc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 13/20 0.56
OPRM1 P35372 7/20 0.56
OPRK1 P41145 3/20 0.56
LTA4H P09960 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22028176 1.00 OPRD1 (0.56) OPRD1OPRM1OPRK1LTA4H
SCHEMBL30053179 0.88 OPRD1 (0.68) OPRD1OPRM1OPRK1LTA4H
SCHEMBL22803631 0.86 LTA4H (0.59) LTA4H
SCHEMBL23463558 0.86 LTA4H (0.59) LTA4H
SCHEMBL20669262 0.85 OPRD1 (0.54) OPRD1OPRM1OPRK1LTA4H
SCHEMBL22030225 0.85 OPRD1 (0.54) OPRD1OPRM1OPRK1LTA4H
SCHEMBL22030230 0.85 OPRD1 (0.54) OPRD1OPRM1OPRK1LTA4H
SCHEMBL22028219 0.85 OPRD1 (0.54) OPRD1OPRM1OPRK1LTA4H
SCHEMBL29992506 0.84 OPRD1 (0.65) OPRD1OPRM1OPRK1LTA4H
SCHEMBL29434570 0.84 OPRD1 (0.61) OPRD1OPRM1OPRK1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3656782-B1 PEPTIDE AMIDE COMPOUND AND PREPARATION METHOD AND MEDICAL USE THEREOF SICHUAN HAISCO PHARMACEUTICAL CO LTD (CN) 2021-12-22 EP disclosed