Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25599910 | 0.91 | GABRG2 (0.40) | MEN1KMT2ASMN1; SMN2KIF11MAPT | |
| SCHEMBL31121937 | 0.79 | CNR1 (0.47) | MEN1KMT2ASMN1; SMN2CA1CA2 | |
| SCHEMBL1866251 | 0.79 | CNR1 (0.47) | MEN1KMT2ASMN1; SMN2CA1CA2 | |
| SCHEMBL20669650 | 0.79 | MEN1 (0.39) | MEN1KMT2ASMN1; SMN2CA1CA2 | |
| SCHEMBL6204840 | 0.74 | CA1 (0.41) | MEN1KMT2ASMN1; SMN2CA1CA2 | |
| SCHEMBL837167 | 0.74 | MEN1 (0.40) | MEN1KMT2ASMN1; SMN2CA1CA2 | |
| Methoxymethane SCHEMBL27841631 | 0.74 | MEN1 (0.45) | MEN1KMT2ASMN1; SMN2CA1CA2 | |
| SCHEMBL826639 | 0.73 | KMT2A (0.45) | MEN1KMT2ASMN1; SMN2CA1CA2 | |
| SCHEMBL3650194 | 0.72 | KCNN4 (0.46) | MEN1KMT2ASMN1; SMN2CA1CA2 | |
| SCHEMBL14650861 | 0.72 | ALDH1A1 (0.46) | MEN1KMT2ASMN1; SMN2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814331-B1 | NOVEL LXR MODULATORS WITH BICYCLIC CORE MOIETY | ORSOBIO INC (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2019016269-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | PHENEX-FXR GMBH (DE) | 2019-01-24 | — | — | WO | disclosed |