Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | C1S | P09871 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28659306 | 0.78 | CA1 (0.50) | CA1CA2CA5ACA9KIF11 | |
| SCHEMBL14650861 | 0.78 | ALDH1A1 (0.46) | CA1CA2CA5ACA9KIF11 | |
| SCHEMBL6204216 | 0.76 | CYP19A1 (0.42) | KIF11ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL6205404 | 0.76 | KIF11 (0.47) | CA1CA2CA9KIF11ALDH1A1 | |
| Methoxymethane SCHEMBL27841631 | 0.75 | MEN1 (0.45) | CA1CA2CA5ACA9KIF11 | |
| SCHEMBL20669652 | 0.74 | MEN1 (0.39) | CA1CA2CA5ACA9KIF11 | |
| SCHEMBL27945120 | 0.73 | CA1 (0.46) | CA1CA2CA5ACA9KIF11 | |
| SCHEMBL27926114 | 0.73 | CA1 (0.46) | CA1CA2CA5ACA9KIF11 | |
| SCHEMBL2154443 | 0.73 | CES1 (0.47) | ALDH1A1MAPK1KMT2ACYP1A2MAPT | |
| SCHEMBL17007995 | 0.73 | CA1 (0.39) | CA1CA2CA5ACA9KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104245786-B | Conjugated polymers | 默克专利股份有限公司 | 2017-01-25 | — | — | CN | disclosed |
| CN-104245786-A | Conjugated polymers | MERCK PATENT GMBH | 2014-12-24 | — | — | CN | disclosed |
| EP-1506175-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097609-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDFG RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-11-27 | — | — | WO | disclosed |