Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | F13A1 | P00488 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 2/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | THPO | P40225 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CASP2 | P42575 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL324690 | 0.92 | CA12 (0.50) | ALOX15CA12F13A1CA2CYP1A2 | |
| SCHEMBL323341 | 0.92 | CA12 (0.50) | ALOX15CA12F13A1CA2CYP1A2 | |
| SCHEMBL15078094 | 0.91 | TDP1 (0.39) | ALOX15CA12F13A1CA2CYP1A2 | |
| SCHEMBL324827 | 0.90 | ALOX15 (0.52) | ALOX15CA12F13A1CA2CYP1A2 | |
| SCHEMBL7513632 | 0.90 | ALOX15 (0.54) | ALOX15CA12F13A1CA2CYP1A2 | |
| SCHEMBL21896480 | 0.89 | CYP2C19 (0.43) | ALOX15CA12F13A1CA2CYP1A2 | |
| SCHEMBL11235151 | 0.88 | TSHR (0.48) | CYP1A2MEN1KMT2ACYP2C19TSHR | |
| SCHEMBL8504211 | 0.87 | RELA (0.50) | ALOX15CA12F13A1CA2CYP1A2 | |
| SCHEMBL7513624 | 0.86 | CA12 (0.52) | ALOX15CA12F13A1CA2CYP1A2 | |
| SCHEMBL6707213 | 0.86 | TDP1 (0.57) | ALOX15CA12F13A1CA2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10752865-B2 | Polyethylene glycol-based composition comprising functionalized siloxane polymers | THE PROCTER & GAMBLE COMPANY (US) | 2020-08-25 | — | — | US | disclosed |
| US-20190024019-A1 | FUNCTIONALIZED SILOXANE POLYMERS AND COMPOSITIONS COMPRISING SAME | THE PROCTER & GAMBLE COMPANY | 2019-01-24 | — | — | US | disclosed |