Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | PDE9A | O76083 | 1/20 | 0.39 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.36 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14898047 | 0.90 | PIK3CD (0.45) | CCR1CCR5CCR8OPRM1OPRL1 | |
| SCHEMBL23365111 | 0.80 | PIK3CD (0.36) | PIK3CDKDM4EALDH1A1MAP3K12ACVR2A | |
| SCHEMBL29979707 | 0.80 | PIK3CD (0.36) | PIK3CDMAP3K12ACVR2ATGFBR2PIK3CA | |
| SCHEMBL23365116 | 0.80 | PIK3CD (0.36) | PIK3CDMAP3K12ACVR2ATGFBR2PIK3CA | |
| SCHEMBL29979625 | 0.80 | PIK3CD (0.36) | PIK3CDKDM4EALDH1A1MAP3K12ACVR2A | |
| SCHEMBL30997801 | 0.80 | CCR1 (0.54) | CCR1CCR5CCR8OPRM1OPRL1 | |
| SCHEMBL827860 | 0.80 | CCR1 (0.54) | CCR1CCR5CCR8OPRM1OPRL1 | |
| SCHEMBL14376103 | 0.80 | NOS3 (0.41) | PIK3CDKDM4EMAP3K12NOS3NOS1 | |
| SCHEMBL25147093 | 0.80 | CHRNA7 (0.40) | PIK3CDPDE9AMAP3K12ACVR2ATGFBR2 | |
| SCHEMBL14349682 | 0.80 | MAP3K12 (0.37) | PIK3CDMAP3K12ACVR2ATGFBR2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019018795-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2019-01-24 | — | — | WO | disclosed |