Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | MAP3K12 | Q12852 | 5/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.32 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23365116 | 1.00 | PIK3CD (0.36) | PIK3CDPIK3CAASIC3PIM1MAP3K12 | |
| SCHEMBL5559958 | 0.90 | PIK3CD (0.43) | PIK3CDPIK3CAASIC3MAP3K12MAPK1 | |
| SCHEMBL30856759 | 0.86 | ASIC3 (0.40) | ASIC3MAPK1ADORA2AADORA1 | |
| SCHEMBL22545239 | 0.86 | ASIC3 (0.40) | ASIC3MAPK1ADORA2AADORA1 | |
| SCHEMBL20676296 | 0.80 | CCR1 (0.42) | PIK3CDPIK3CAPIM1MAP3K12ACVR2A | |
| SCHEMBL23365111 | 0.80 | PIK3CD (0.36) | PIK3CDPIK3CAPIM1MAP3K12PRMT5 | |
| SCHEMBL29979625 | 0.80 | PIK3CD (0.36) | PIK3CDPIK3CAPIM1MAP3K12PRMT5 | |
| SCHEMBL12068738 | 0.80 | ADORA2A (0.45) | ASIC3PIM1MAPK1ADORA2AADORA1 | |
| SCHEMBL14375570 | 0.77 | MAP3K12 (0.38) | PIK3CDPIK3CAPIM1MAP3K12ACVR2A | |
| SCHEMBL4183278 | 0.77 | CHRNA7 (0.42) | ASIC3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4058016-A1 | THIOPHENE COMPOUNDS WITH CYCLIC AMIDES, AND USES THEREOF | Capulus Therapeutics, LLC (US) | 2022-09-21 | — | — | EP | disclosed |