Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.41 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4261970 | 0.78 | HPGDS (0.52) | HPGDSTLR9TLR8TLR7SMN1; SMN2 | |
| Bromide SCHEMBL2984287 | 0.77 | HPGDS (0.51) | HPGDSTLR9TLR8TLR7SMN1; SMN2 | |
| SCHEMBL4257716 | 0.76 | HPGDS (0.53) | HPGDSHTR2AHTR2CMEN1KMT2A | |
| SCHEMBL4262081 | 0.76 | CYP1A1 (0.59) | HPGDSTLR9TLR7SMN1; SMN2ALDH1A1 | |
| Bromide SCHEMBL2981940 | 0.75 | HPGDS (0.52) | HPGDSL3MBTL1HTR2AHTR2CMEN1 | |
| Bromide SCHEMBL2985795 | 0.75 | CYP1A1 (0.57) | HPGDSTLR9TLR7SMN1; SMN2ALDH1A1 | |
| SCHEMBL27713695 | 0.74 | HPGDS (0.45) | HPGDSBAZ2AEPHA2KDREPHB4 | |
| SCHEMBL12620740 | 0.72 | BAZ2A (0.47) | HPGDSBAZ2ASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL4257174 | 0.71 | RAB9A (0.60) | HPGDSSMN1; SMN2LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL4255919 | 0.70 | JAK2 (0.44) | HPGDSBAZ2ASMN1; SMN2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019018795-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2019-01-24 | — | — | WO | disclosed |