SCHEMBL2067685

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6846692	1.00	FURIN (0.44)	FURINALDH1A1LMNACES2CES1
	SCHEMBL15784371	0.82	CYP1A2 (0.33)	FURINALDH1A1LMNACES2CES1
	SCHEMBL2704783	0.80	MEN1 (0.47)	FURINALDH1A1LMNASMN1; SMN2MAPT
	SCHEMBL15053148	0.80	CYP19A1 (0.50)	FURINALDH1A1LMNASMN1; SMN2NPC1
	SCHEMBL10802341	0.79	FURIN (0.61)	FURINALDH1A1LMNACES2CES1
	SCHEMBL23837603	0.78	LMNA (0.53)	FURINALDH1A1LMNACES2CES1
	SCHEMBL15053824	0.78	LMNA (0.53)	FURINALDH1A1LMNACES2CES1
	SCHEMBL5415127	0.78	MAPT (0.50)	FURINALDH1A1CES2CES1TDP1
	SCHEMBL6734907	0.78	LMNA (0.61)	FURINALDH1A1LMNACES2CES1
	SCHEMBL6053302	0.78	MAPT (0.50)	FURINALDH1A1CES2CES1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.