Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5415127 | 1.00 | MAPT (0.50) | MAPTNOS1CA1CA2CA4 | |
| SCHEMBL2067685 | 0.78 | FURIN (0.44) | MAPTCA9MEN1KMT2AALDH1A1 | |
| SCHEMBL2704783 | 0.78 | MEN1 (0.47) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL15053148 | 0.78 | CYP19A1 (0.50) | MAPTNOS1MEN1KMT2AL3MBTL1 | |
| SCHEMBL4140209 | 0.78 | CA9 (0.50) | MAPTNOS1CA9MEN1KMT2A | |
| SCHEMBL24329691 | 0.78 | MEN1 (0.47) | MAPTNOS1CA1CA2CA4 | |
| SCHEMBL6846692 | 0.78 | FURIN (0.44) | MAPTCA9MEN1KMT2AALDH1A1 | |
| SCHEMBL4140208 | 0.78 | CA9 (0.50) | MAPTNOS1CA9MEN1KMT2A | |
| SCHEMBL6734907 | 0.76 | LMNA (0.61) | MAPTCA1CA2CA4CA9 | |
| SCHEMBL6734905 | 0.76 | LMNA (0.61) | MAPTCA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1668105-A1 | HIGH ALCOHOL CONTENT GEL-LIKE AND FOAMING COMPOSITIONS | Ethena Healthcare Inc. (CA) | 2006-06-14 | — | — | EP | disclosed |
| EP-1272223-B1 | THERAPEUTIC AND DIAGNOSTIC LIGAND SYSTEMS COMPRISING TRANSPORT MOLECULE BINDING PROPERTIES AND MEDICAMENTS CONTAINING THE SAME | KTB TUMORFORSCHUNGS GMBH (DE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005030917-A1 | HIGH ALCOHOL CONTENT GEL-LIKE AND FOAMING COMPOSITIONS | ETHENA HEALTHCARE INC. (CA) | 2005-04-07 | — | — | WO | disclosed |
| US-20030185793-A1 | Therapeutic and diagnostic ligand systems comprising transport molecule binding properties and medicaments containing the same | Vergell Medical S.A. (CH) | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030185793-A1 | Therapeutic and diagnostic ligand systems comprising transport molecule binding properties and medicaments containing the same | SLCO1B1, SLCO1B3, SLCO1A2 | MAPT 1735/4885NOS1 3017/4885CA1 2116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.