SCHEMBL20677265

SCHEMBL20677265

C=C[Si](C)(C)N(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.47
TSHR P16473 3/20 0.45
ALDH1A1 P00352 3/20 0.45
LMNA P02545 2/20 0.39
GAA P10253 1/20 0.39
CARM1 Q86X55 1/20 0.37
PRMT6 Q96LA8 1/20 0.37
PRMT8 Q9NR22 1/20 0.37
CYP2C19 P33261 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
SLC6A2 P23975 1/20 0.36
HTR2A P28223 1/20 0.36
SLC6A4 P31645 1/20 0.36
ADRA1A P35348 1/20 0.36
OPRK1 P41145 1/20 0.36
SLC6A3 Q01959 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17995601 0.84 AOC3 (0.47) AOC3TSHRALDH1A1LMNAGAA
SCHEMBL9804706 0.76 TSHR (0.54) AOC3TSHRALDH1A1LMNACARM1
SCHEMBL28365177 0.76 AOC3 (0.42) AOC3TSHRALDH1A1LMNACARM1
SCHEMBL19828334 0.75 AOC3 (0.39) AOC3TSHRALDH1A1GAAL3MBTL1
SCHEMBL28280605 0.75 TSHR (0.48) AOC3TSHRALDH1A1LMNACARM1
SCHEMBL3776692 0.73 ALDH1A1 (0.42) AOC3TSHRALDH1A1GAACARM1
SCHEMBL19712144 0.72 ALDH1A1 (0.34) AOC3TSHRALDH1A1LMNAGAA
SCHEMBL15360536 0.72 ALDH1A1 (0.37) AOC3TSHRALDH1A1GAACYP2C19
SCHEMBL18779656 0.72 ALDH1A1 (0.37) AOC3TSHRALDH1A1LMNAGAA
SCHEMBL10628151 0.71 TSHR (0.50) AOC3TSHRALDH1A1LMNACARM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10954330-B2 Use of specific aminosilyl monomers in the manufacture of rubber TRINSEO EUROPE GMBH (CH) 2021-03-23 US disclosed
US-20200377636-A1 Use of Specific Aminosilyl Monomers in the Manufacture of Rubber SYNTHOS DWORY 7 SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (PL) 2020-12-03 US disclosed
WO-2019020752-A1 USE OF SPECIFIC AMINOSILYL MONOMERS IN THE MANUFACTURE OF RUBBER TRINSEO EUROPE GMBH (CH) 2019-01-31 WO disclosed
EP-3434699-A1 USE OF SPECIFIC AMINOSILYL MONOMERS IN THE MANUFACTURE OF RUBBER Trinseo Europe GmbH (CH) 2019-01-30 EP disclosed