SCHEMBL20680463

SCHEMBL20680463

CSc1ccc(O)c(C(C)(C)C)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.57
ALOX15 P16050 6/20 0.57
HSD17B10 Q99714 2/20 0.57
LMNA P02545 2/20 0.57
NR1I2 O75469 1/20 0.57
CYP2C9 P11712 1/20 0.57
MIF P14174 1/20 0.57
TYR P14679 1/20 0.57
HTT P42858 1/20 0.57
NFE2L2 Q16236 1/20 0.57
MAPT P10636 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
KDM4E B2RXH2 1/20 0.50
CYP1A2 P05177 1/20 0.50
ATP2A2 P16615 1/20 0.50
ATP2A3 Q93084 1/20 0.50
MCL1 Q07820 1/20 0.48
HPN P05981 1/20 0.45
SIRT5 Q9NXA8 1/20 0.45
TDP1 Q9NUW8 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL316680 0.85 ALDH1A1 (0.59) ALDH1A1ALOX15HSD17B10LMNANR1I2
SCHEMBL9340912 0.85 ALDH1A1 (0.59) ALDH1A1ALOX15HSD17B10LMNANR1I2
SCHEMBL10626842 0.83 ALOX15 (0.61) ALDH1A1ALOX15HSD17B10LMNANR1I2
SCHEMBL11218507 0.82 MCL1 (0.47) ALDH1A1ALOX15HSD17B10LMNANR1I2
SCHEMBL11553732 0.82 ALDH1A1 (0.55) ALDH1A1ALOX15HSD17B10LMNANR1I2
SCHEMBL27878255 0.80 ALDH1A1 (0.53) ALDH1A1ALOX15HSD17B10LMNANR1I2
SCHEMBL9788696 0.80 ALDH1A1 (0.53) ALDH1A1ALOX15HSD17B10LMNANR1I2
SCHEMBL7160236 0.77 ALDH1A1 (0.50) ALDH1A1ALOX15HSD17B10LMNANR1I2
SCHEMBL9818839 0.77 CA2 (0.50) ALDH1A1ALOX15HSD17B10LMNANR1I2
SCHEMBL11588522 0.76 ALDH1A1 (0.48) ALDH1A1ALOX15HSD17B10LMNANR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3658616-A1 HALOGEN-FREE SULPHONIC ACID ESTER AND/OR SULPHINIC ACID ESTER AS FLAME RETARDANT, FLAME RETARDANT SYNERGISTS AND RADICAL GENERATORS IN PLASTICS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2020-06-03 EP disclosed
WO-2019020699-A1 HALOGEN-FREE SULPHONIC ACID ESTER AND/OR SULPHINIC ACID ESTER AS FLAME RETARDANT, FLAME RETARDANT SYNERGISTS AND RADICAL GENERATORS IN PLASTICS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2019-01-31 WO disclosed
CN-1820054-B Polycondensates as dyeing promoters for hydrophobic polymer articles CIBA SC HOLDING AG 2012-11-14 CN disclosed
CN-101437886-B Derivatives of pyrimidines as flame retardants CIBA HOLDING INC 2011-11-09 CN disclosed
CN-101437886-A Derivatives of pyrimidines as flame retardants CIBA HOLDING INC (CH) 2009-05-20 CN disclosed
CN-100482726-C Highly compatible and non-migratory polymeric UV absorbers CIBA SC HOLDING AG (CH) 2009-04-29 CN disclosed
CN-101421343-A Stabilized spandex compositions CYTEC TECH CORP (US) 2009-04-29 CN disclosed
CN-100439434-C Flame retardant compositions CIBA SC HOLDING AG (CH) 2008-12-03 CN disclosed
CN-101291982-A Material with antibacterial and antifungal properties CIBA HOLDING INC (CH) 2008-10-22 CN disclosed
CN-100393620-C Process for preparing polyolefin nanocomposites POLYMERS AUSTRALIA PTY LTD (AU) 2008-06-11 CN disclosed
CN-1461767-A Agricultural products SIBA SPECIALTY CHEMCALS HOLDIN (CH) 2003-12-17 CN disclosed
CN-1082066-C Synergistic stabilizer mixture CIBA SC HOLDING AG (CH) 2002-04-03 CN disclosed
CN-1079809-C Synergistic stabilizer mixture CIBA SC HOLDING AG (CH) 2002-02-27 CN disclosed
CN-1074017-C Method for increasing molecular weight of polycondensates CIBA GEIGY AG (CH) 2001-10-31 CN disclosed
CN-1036928-C Oligomeric HALS phosphites and HALS phosphonites as stabilisers CIBA SPECIAL CHEMICAL CO LTD (CH) 1998-01-07 CN disclosed
CN-1162325-A Method for increasing molecular weight of polycondensates CIBA GEIGY AG (CH) 1997-10-15 CN disclosed
CN-1137541-A Synergistic stabilizer mixture CIBA GEIGY AG (CH) 1996-12-11 CN disclosed
CN-1136048-A Synergistic stabilizer mixture CIBA GEIGY AG (CH) 1996-11-20 CN disclosed
CN-1114653-A Oligomeric hals phophites and hals phosphonites as stabilisers CIBA GEIGY AG (CH) 1996-01-10 CN disclosed
CN-1092785-A Oligomeric HALS phosphorous acid ester and HALS phosphinate with used as stabilizers CIBA GEIGY AG (CH) 1994-09-28 CN disclosed