Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 8/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20680745 | 0.81 | MAPK1 (0.47) | FGFR1ALDH1A1 | |
| SCHEMBL20698308 | 0.79 | HSD11B1 (0.36) | FGFR1KCNH2HCAR1MAPK14 | |
| SCHEMBL20698174 | 0.79 | L3MBTL1 (0.32) | L3MBTL1 | |
| SCHEMBL20698173 | 0.79 | SIK1 (0.34) | FGFR1KCNH2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL20697928 | 0.78 | HSD11B1 (0.41) | FGFR1KCNH2IGF1R | |
| SCHEMBL20698203 | 0.78 | FGFR1 (0.35) | FGFR1KCNH2HCAR1ALDH1A1KMT2A | |
| SCHEMBL20697990 | 0.77 | FGFR1 (0.39) | FGFR1KCNH2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL20697989 | 0.74 | FGFR1 (0.39) | FGFR1KCNH2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL20698122 | 0.73 | FGFR1 (0.41) | FGFR1KCNH2KMT2AMEN1 | |
| SCHEMBL20697939 | 0.71 | MAPK1 (0.41) | FGFR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019020981-A1 | PYRAZOLE, ISOTHIAZOLE AND ISOXAZOLE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | REDAG CROP PROTECTION LTD. (GB) | 2019-01-31 | — | — | WO | disclosed |