SCHEMBL20682155

SCHEMBL20682155

CC(C)(CO)OC(=O)c1ccc(C(=O)c2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.47
CD274 Q9NZQ7 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.45
KDM4E B2RXH2 1/20 0.45
MAPT P10636 3/20 0.45
MEN1 O00255 1/20 0.45
LMNA P02545 1/20 0.45
RAB9A P51151 1/20 0.45
KMT2A Q03164 1/20 0.45
EGFR P00533 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
POLB P06746 1/20 0.43
MAPK1 P28482 1/20 0.43
GAA P10253 1/20 0.43
CDC25B P30305 1/20 0.42
ATM Q13315 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5085501 0.85 CYP2D6 (0.53) SMN1; SMN2MAPTLMNARAB9AKMT2A
SCHEMBL22854416 0.83 ELANE (0.43) MAPTMEN1LMNAKMT2AMAPK1
SCHEMBL14506869 0.83 SMN1; SMN2 (0.51) PDCD1CD274SMN1; SMN2KDM4EMAPT
SCHEMBL28561084 0.80 ALDH1A1 (0.47) SMN1; SMN2MAPTKMT2ACA12CA1
SCHEMBL6355405 0.79 CA12 (0.63) PDCD1CD274SMN1; SMN2KDM4EMAPT
SCHEMBL19491953 0.76 PPARA (0.39) PDCD1CD274SMN1; SMN2KDM4EMAPT
SCHEMBL9800535 0.75 ALDH1A1 (0.56) LMNARAB9AL3MBTL1ATMCA12
SCHEMBL27796550 0.74 PDCD1 (0.53) PDCD1CD274SMN1; SMN2KDM4EMAPT
SCHEMBL232724 0.74 RAB9A (0.74) SMN1; SMN2MAPTMEN1LMNARAB9A
SCHEMBL17736345 0.74 KDM4E (0.62) PDCD1CD274SMN1; SMN2KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10189930-B2 Polymeric photoinitiators ALLNEX BELGIUM S.A. (BE) 2019-01-29 US disclosed