Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17901092 | 1.00 | CTSK (0.42) | CTSKCTSSKMT2ACA1CA2 | |
| SCHEMBL20682983 | 0.95 | KMT2A (0.46) | CTSKCTSSKMT2ACA1CA2 | |
| SCHEMBL17901296 | 0.95 | KMT2A (0.46) | CTSKCTSSKMT2ACA1CA2 | |
| SCHEMBL17904803 | 0.86 | KMT2A (0.46) | CTSKCTSSKMT2ACA1CA2 | |
| SCHEMBL20682989 | 0.85 | KMT2A (0.45) | CTSKCTSSKMT2ACA1CA2 | |
| SCHEMBL17901093 | 0.85 | KMT2A (0.45) | CTSKCTSSKMT2ACA1CA2 | |
| SCHEMBL17905125 | 0.84 | KMT2A (0.48) | CTSKCTSSKMT2ACA1CA2 | |
| SCHEMBL17905501 | 0.81 | KMT2A (0.46) | CTSKCTSSKMT2ACA1CA2 | |
| SCHEMBL17904993 | 0.81 | CTSK (0.43) | CTSKCTSSKMT2ACTSLCTSB | |
| SCHEMBL20682888 | 0.80 | CA1 (0.42) | CTSKCTSSKMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10188109-B2 | Picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10188109-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | CTSK 2808/4885CTSS 1597/4885KMT2A 3102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.