Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 17/20 | 0.57 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.55 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.55 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22533870 | 0.88 | KDM4E (0.50) | CHEK2PKN1PKN2MLKL | |
| SCHEMBL18785691 | 0.86 | MLKL (0.68) | CHEK2MLKL | |
| SCHEMBL17356144 | 0.85 | F10 (0.60) | — | |
| SCHEMBL4249669 | 0.82 | KDM4E (0.61) | MLKL | |
| SCHEMBL18237000 | 0.82 | HDAC6 (0.65) | MLKL | |
| SCHEMBL27332257 | 0.80 | KDM4E (0.51) | MLKL | |
| SCHEMBL6368273 | 0.80 | CHEK2 (0.47) | CHEK2PKN1PKN2 | |
| SCHEMBL7428472 | 0.80 | HSP90AA1 (0.73) | CHEK2PKN1PKN2 | |
| SCHEMBL12685844 | 0.78 | ABL1 (0.68) | CHEK2PKN1PKN2 | |
| SCHEMBL3416768 | 0.78 | CHEK2 (0.61) | CHEK2PKN1PKN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10189830-B2 | Alkyl-heteroaryl substituted quinone derivatives for treatment of oxidative stress disorders | BIOELECTRON TECHNOLOGY CORPORATION (US) | 2019-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10189830-B2 | Alkyl-heteroaryl substituted quinone derivatives for treatment of oxidative stress disorders | NQO1, COQ8A, NDUFAB1 | CHEK2 933/4885PKN1 3066/4885PKN2 2531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.