Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MLKL | Q8NB16 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798790 | 0.75 | SCN10A (0.69) | SCN10AALDH1A1ALOX15CYP1A2KDM4E | |
| SCHEMBL20683080 | 0.75 | KDM4E (0.49) | ALDH1A1KDM4EHSD17B10HTTHPGD | |
| SCHEMBL23815820 | 0.72 | SCN10A (0.71) | SCN10AALDH1A1ALOX15CYP1A2KDM4E | |
| SCHEMBL24998835 | 0.71 | SCN10A (0.56) | SCN10AALDH1A1ALOX15CYP1A2KDM4E | |
| SCHEMBL4240625 | 0.70 | ALDH1A1 (0.63) | SCN10AALDH1A1ALOX15CYP1A2KDM4E | |
| SCHEMBL14197238 | 0.68 | KDM4E (0.57) | SCN10AALDH1A1ALOX15CYP1A2KDM4E | |
| SCHEMBL2706618 | 0.67 | KDM4E (0.57) | SCN10ACYP1A2KDM4ELMNAHSD17B10 | |
| SCHEMBL890080 | 0.66 | CYP1A2 (0.75) | SCN10AALDH1A1ALOX15CYP1A2KDM4E | |
| SCHEMBL10141265 | 0.66 | ALDH1A1 (0.60) | SCN10AALDH1A1ALOX15CYP1A2KDM4E | |
| SCHEMBL18930199 | 0.65 | SCN10A (0.49) | SCN10AALDH1A1ALOX15CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10189830-B2 | Alkyl-heteroaryl substituted quinone derivatives for treatment of oxidative stress disorders | BIOELECTRON TECHNOLOGY CORPORATION (US) | 2019-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10189830-B2 | Alkyl-heteroaryl substituted quinone derivatives for treatment of oxidative stress disorders | NQO1, COQ8A, NDUFAB1 | SCN10A 2984/4885ALDH1A1 605/4885ALOX15 290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.