Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 8/20 | 0.48 |
| ▸ | ARG2 | P78540 | 7/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12292270 | 0.84 | KCNH2 (0.51) | CYP2D6KCNH2CHRM4CHRM3SIGMAR1 | |
| SCHEMBL895007 | 0.83 | ARG1 (0.71) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL894875 | 0.82 | ARG1 (0.69) | ARG1ARG2CHRM4CHRM3 | |
| SCHEMBL20683338 | 0.82 | DRD2 (0.54) | DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL894979 | 0.81 | ARG1 (0.68) | ARG1ARG2CHRM4CHRM3 | |
| SCHEMBL20683323 | 0.79 | ARG1 (0.62) | ARG1ARG2 | |
| SCHEMBL20683413 | 0.79 | ARG1 (0.58) | ARG1ARG2 | |
| SCHEMBL20683391 | 0.77 | ARG1 (0.63) | ARG1ARG2 | |
| SCHEMBL20683331 | 0.77 | KCNA3 (0.48) | ARG1ARG2SIGMAR1DRD2DRD4 | |
| SCHEMBL20683388 | 0.77 | ARG1 (0.47) | ARG1ARG2KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560978-B1 | INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS | MARS INC (US) | 2019-01-30 | — | — | EP | disclosed |