Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ARG1 | P05089 | 1/20 | 0.48 |
| ▸ | ARG2 | P78540 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL894946 | 0.89 | ARG1 (0.62) | LMNAKDM4EABL1ALDH1A1MEN1 | |
| SCHEMBL30169855 | 0.89 | ARG1 (0.62) | LMNAKDM4EABL1ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL895133 | 0.88 | ARG1 (0.61) | LMNAKDM4EABL1ALDH1A1MEN1 | |
| SCHEMBL20683534 | 0.85 | ARG1 (0.50) | KDM4EARG1ARG2MAPT | |
| SCHEMBL20683420 | 0.85 | FFAR4 (0.50) | KDM4EALDH1A1ARG1ARG2MAPT | |
| SCHEMBL20683476 | 0.81 | MAPT (0.52) | LMNAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL20683387 | 0.80 | ARG1 (0.43) | ALDH1A1MEN1KMT2AARG1ARG2 | |
| SCHEMBL20683451 | 0.77 | ADRB1 (0.47) | KMT2AARG1ARG2CHRM4 | |
| SCHEMBL895072 | 0.75 | ARG1 (0.66) | KDM4EARG1ARG2MAPT | |
| SCHEMBL30170023 | 0.75 | ARG1 (0.66) | KDM4EARG1ARG2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560978-B1 | INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS | MARS INC (US) | 2019-01-30 | — | — | EP | disclosed |