Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 8/20 | 0.60 |
| ▸ | ARG2 | P78540 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20683360 | 0.88 | ARG1 (0.68) | ARG1ARG2MEN1KMT2ATDP1 | |
| SCHEMBL20683406 | 0.85 | CHRM2 (0.49) | ARG1ARG2MEN1KMT2ASCN8A | |
| SCHEMBL894921 | 0.82 | ARG1 (0.79) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL895047 | 0.81 | ARG1 (0.77) | ARG1ARG2 | |
| SCHEMBL20683425 | 0.80 | ARG1 (0.64) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL895023 | 0.80 | ARG1 (0.76) | ARG1ARG2 | |
| SCHEMBL3438918 | 0.76 | KMT2A (0.53) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL20683349 | 0.75 | MTNR1A (0.48) | SCN8ACHRM2 | |
| SCHEMBL20683356 | 0.75 | ARG1 (0.45) | ARG1ARG2 | |
| SCHEMBL894176 | 0.75 | ARG1 (1.00) | ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560978-B1 | INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS | MARS INC (US) | 2019-01-30 | — | — | EP | disclosed |