Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6925716 | 0.78 | GRM1 (0.49) | GRM1NR1H2NR1H3 | |
| SCHEMBL28752505 | 0.75 | MGLL (0.48) | HPGDHTTTDP1ALDH1A1 | |
| SCHEMBL28396965 | 0.73 | CA9 (0.47) | GRM1GRM4ALDH1A1HSD17B10 | |
| SCHEMBL17696374 | 0.71 | HSD17B10 (0.53) | KDM4EHPGDLMNAGAAHTT | |
| SCHEMBL21474631 | 0.70 | DPP4 (0.37) | DPP4KDM4EHPGDTDP1NR1H2 | |
| SCHEMBL28407462 | 0.70 | GRM1 (0.48) | GRM1GRM4 | |
| SCHEMBL28398982 | 0.70 | AR (0.49) | GRM1GRM4 | |
| SCHEMBL28399876 | 0.68 | ALDH1A1 (0.41) | DPP4GRM1KDM4EHPGDLMNA | |
| SCHEMBL21478341 | 0.67 | MEN1 (0.38) | DPP4TYMSHPGDALDH1A1 | |
| SCHEMBL21478347 | 0.66 | MEN1 (0.39) | TYMSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3087069-B1 | COMPOUNDS USEFUL AS CCR9 MODULATORS | NORGINE BV (NL) | 2019-01-30 | — | — | EP | disclosed |