Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20686277 | 0.88 | — | — | |
| SCHEMBL20686168 | 0.87 | TP53 (0.30) | TP53 | |
| SCHEMBL17275693 | 0.79 | ALDH1A1 (0.37) | TP53 | |
| SCHEMBL20686187 | 0.78 | — | — | |
| SCHEMBL20686158 | 0.77 | ALDH1A1 (0.35) | — | |
| SCHEMBL20686173 | 0.77 | UBE2T (0.32) | TP53 | |
| SCHEMBL17275860 | 0.76 | PROKR1 (0.33) | TP53 | |
| SCHEMBL20686268 | 0.74 | ALDH1A1 (0.36) | — | |
| SCHEMBL20686166 | 0.73 | PROKR1 (0.32) | — | |
| SCHEMBL15579196 | 0.73 | TP53 (0.44) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3145923-B1 | INDOLIN-2-ONE AND 1,3-DIHYDRO-PYRROLO[3,2-C]PYRIDIN-2-ONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2019-01-30 | — | — | EP | disclosed |