Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20080425 | 0.91 | PDK2 (0.51) | PDK2MAOAMAOBARPTGDR2 | |
| SCHEMBL20691366 | 0.89 | PDK2 (0.49) | PDK2MAOAMAOBMDM2 | |
| SCHEMBL21922497 | 0.89 | PDK2 (0.39) | PDK2ARBACE1MDM2ABCC9 | |
| SCHEMBL20691493 | 0.86 | PDK2 (0.51) | PDK2ARPTGDR2 | |
| SCHEMBL22106373 | 0.86 | PDK2 (0.52) | PDK2MAOAMAOBBACE1MDM2 | |
| SCHEMBL22895212 | 0.86 | PDK2 (0.55) | PDK2MAOAMAOBPTGDR2TSHR | |
| SCHEMBL18907228 | 0.82 | PDK2 (0.44) | PDK2MAOAMAOBARBACE1 | |
| SCHEMBL29811010 | 0.82 | PDK2 (0.44) | PDK2MAOAMAOBBACE1TSHR | |
| SCHEMBL15763537 | 0.82 | PDK2 (0.44) | PDK2MAOAMAOBBACE1TSHR | |
| SCHEMBL21701932 | 0.81 | PDK2 (0.45) | PDK2BACE1AKR1A1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11542237-B2 | Fluorene derivative and organic light emitting device comprising same | LG CHEM, LTD. (KR) | 2023-01-03 | — | — | US | disclosed |
| EP-3896061-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | Solus Advanced Materials Co., Ltd. (KR) | 2021-10-20 | — | — | EP | disclosed |
| US-20200131138-A1 | FLUORENE DERIVATIVE AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2020-04-30 | — | — | US | disclosed |
| WO-2019022455-A1 | FLUORENE DERIVATIVE AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | 주식회사 엘지화학 | 2019-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11542237-B2 | Fluorene derivative and organic light emitting device comprising same | CRY1, CRY2, LEF1 | PDK2 2091/4885MAOA 628/4885MAOB 565/4885 |
| US-20200131138-A1 | FLUORENE DERIVATIVE AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | CRY1, CRY2, LEF1 | PDK2 2091/4885MAOA 628/4885MAOB 565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.