Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 5/20 | 0.32 |
| ▸ | DNPH1 | O43598 | 3/20 | 0.32 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22349173 | 1.00 | TYMP (0.33) | TYMPSLC29A1DNPH1METTL3NT5E | |
| SCHEMBL20691938 | 0.87 | HIF1A (0.33) | TYMPSLC29A1 | |
| SCHEMBL21263982 | 0.84 | TAS1R3 (0.38) | TYMPSLC29A1 | |
| SCHEMBL20691457 | 0.82 | DNPH1 (0.32) | SLC29A1DNPH1 | |
| SCHEMBL20691327 | 0.79 | SLC29A1 (0.31) | SLC29A1DNPH1 | |
| SCHEMBL20692221 | 0.78 | P2RX3 (0.36) | TYMP | |
| SCHEMBL20691298 | 0.77 | AHCY (0.37) | TYMP | |
| SCHEMBL22349203 | 0.77 | STING1 (0.38) | TYMP | |
| SCHEMBL24680698 | 0.76 | DNPH1 (0.33) | TYMPSLC29A1DNPH1 | |
| SCHEMBL20692131 | 0.76 | SLC29A1 (0.35) | TYMPSLC29A1METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3658565-B1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2022-11-09 | — | — | EP | disclosed |
| WO-2019023459-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-01-31 | — | — | WO | disclosed |