Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 6/20 | 0.56 |
| ▸ | GABBR1 | Q9UBS5 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20694143 | 1.00 | GABBR2 (0.56) | GABBR2GABBR1LMNATSHRCYP2C9 | |
| SCHEMBL10507284 | 0.86 | GABBR2 (0.64) | GABBR2GABBR1LMNATSHRCYP2C9 | |
| Hydrochloric Acid SCHEMBL10681987 | 0.84 | GABBR2 (0.62) | GABBR2GABBR1LMNATSHRCYP2C9 | |
| SCHEMBL6278627 | 0.78 | GABBR2 (0.56) | GABBR2GABBR1LMNATSHRCYP2C9 | |
| SCHEMBL19803214 | 0.78 | GABBR2 (0.56) | GABBR2GABBR1LMNATSHRCYP2C9 | |
| SCHEMBL19803301 | 0.78 | GABBR2 (0.56) | GABBR2GABBR1LMNATSHRCYP2C9 | |
| SCHEMBL7396004 | 0.78 | GABBR2 (0.61) | GABBR2GABBR1LMNATSHRCYP2C9 | |
| SCHEMBL9779274 | 0.78 | GABBR2 (0.61) | GABBR2GABBR1LMNATSHRCYP2C9 | |
| SCHEMBL11436391 | 0.77 | GABBR2 (0.55) | GABBR2GABBR1SLC6A4SLC6A3TAAR1 | |
| SCHEMBL24878696 | 0.75 | GABBR2 (0.53) | GABBR2GABBR1LMNATSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250177330-A1 | Use of Thiol Compounds to Treat Neurological Disease | MERCAPTOR DISCOVERIES, INC. | 2025-06-05 | — | — | US | disclosed |
| US-12128014-B2 | Use of thiol compounds to treat neurological disease | MERCAPTOR DISCOVERIES, INC. (US) | 2024-10-29 | — | — | US | disclosed |
| EP-3615013-B1 | THIOL COMPOUNS FOR TREATING ACUTE TRAUMATIC BRAIN INJURY | MERCAPTOR DISCOVERIES INC (US) | 2024-08-14 | — | — | EP | disclosed |
| US-20230115413-A1 | Use of Thiol Compounds to Treat Neurological Disease | ZANKEL, TODD C, MR | 2023-04-13 | — | — | US | disclosed |
| US-20230115413-A1 | Use of Thiol Compounds to Treat Neurological Disease | ZANKEL, TODD C, MR | 2023-04-13 | — | — | US | disclosed |
| US-20210069129-A1 | Use of Thiol Compounds to Treat Neurological Disease | ZANKEL, TODD C, MR | 2021-03-11 | — | — | US | disclosed |
| US-20210069129-A1 | Use of Thiol Compounds to Treat Neurological Disease | ZANKEL, TODD C, MR | 2021-03-11 | — | — | US | disclosed |
| CN-110996929-A | Treatment of neurological disorders with thiol compounds | 麦凯特探索公司 | 2020-04-10 | — | — | CN | disclosed |
| EP-3615013-A1 | USE OF THIOL COMPOUNDS TO TREAT NEUROLOGICAL DISEASE | Mercaptor Discoveries, Inc. (US) | 2020-03-04 | — | — | EP | disclosed |
| US-20190029977-A1 | Use of Thiol Compounds to Treat Neurological Disease | ZANKEL, TODD C, MR | 2019-01-31 | — | — | US | disclosed |
| US-20190029977-A1 | Use of Thiol Compounds to Treat Neurological Disease | ZANKEL, TODD C, MR | 2019-01-31 | — | — | US | disclosed |
| WO-2018200527-A1 | USE OF THIOL COMPOUNDS TO TREAT NEUROLOGICAL DISEASE | MERCAPTOR DISCOVERIES, INC. (US) | 2018-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12128014-B2 | Use of thiol compounds to treat neurological disease | TST, NLN, SLC7A11 | GABBR2 620/4885GABBR1 677/4885LMNA 4730/4885 |
| US-20190029977-A1 | Use of Thiol Compounds to Treat Neurological Disease | TST, NLN, SLC7A11 | GABBR2 620/4885GABBR1 677/4885LMNA 4730/4885 |
| US-20230115413-A1 | Use of Thiol Compounds to Treat Neurological Disease | TST, NLN, SLC7A11 | GABBR2 620/4885GABBR1 677/4885LMNA 4730/4885 |
| US-20210069129-A1 | Use of Thiol Compounds to Treat Neurological Disease | TST, NLN, SLC7A11 | GABBR2 620/4885GABBR1 677/4885LMNA 4730/4885 |
| US-20250177330-A1 | Use of Thiol Compounds to Treat Neurological Disease | TST, NLN, SLC7A11 | GABBR2 620/4885GABBR1 677/4885LMNA 4730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.