Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.45 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5864989 | 0.93 | MALT1 (0.48) | MALT1SCDKDM4EALDH1A1MEN1 | |
| SCHEMBL20694278 | 0.84 | PDE10A (0.39) | SCDPDE10AALDH1A1PDE3BPDE3A | |
| SCHEMBL20694380 | 0.82 | HTR2C (0.45) | SCDPDE10AALDH1A1MAPK1LMNA | |
| SCHEMBL20694381 | 0.82 | ALDH1A1 (0.45) | MALT1SCDPDE10AALDH1A1MAPT | |
| SCHEMBL5864916 | 0.82 | SCD (0.56) | SCDALDH1A1MEN1KMT2A | |
| SCHEMBL20694226 | 0.78 | ALDH1A1 (0.44) | SCDPDE10AKDM4EALDH1A1PIK3CD | |
| SCHEMBL10107364 | 0.78 | DRD2 (0.51) | PIK3CDPIK3CA | |
| SCHEMBL20694378 | 0.77 | ACACB (0.46) | PDE10AALDH1A1LMNAMAPT | |
| SCHEMBL20694348 | 0.77 | ALDH1A1 (0.50) | MALT1SCDKDM4EALDH1A1MAPT | |
| SCHEMBL5864969 | 0.77 | ALDH1A1 (0.43) | SCDALDH1A1MAPK1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019022223-A1 | CYCLIC AMINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | 東レ株式会社 | 2019-01-31 | — | — | WO | disclosed |