Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 11/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5864989 | 0.86 | MALT1 (0.48) | SCDMEN1KMT2AALDH1A1 | |
| SCHEMBL20694232 | 0.82 | MALT1 (0.45) | SCDMEN1KMT2AALDH1A1 | |
| SCHEMBL5864962 | 0.82 | SCD (0.42) | SCDALDH1A1HTTCSNK2A1 | |
| SCHEMBL20694348 | 0.82 | ALDH1A1 (0.50) | SCDALDH1A1HTTCSNK2A1 | |
| SCHEMBL5864969 | 0.82 | ALDH1A1 (0.43) | SCDALDH1A1HTTCSNK2A1 | |
| SCHEMBL5864926 | 0.81 | TRPV6 (0.42) | SCD | |
| SCHEMBL5865147 | 0.80 | SCD (0.67) | SCDMEN1KMT2AALDH1A1 | |
| SCHEMBL20694168 | 0.79 | ALDH1A1 (0.43) | SCDALDH1A1HTTCSNK2A1 | |
| SCHEMBL25769675 | 0.79 | CSNK2A1 (0.54) | ALDH1A1HTTCSNK2A1 | |
| SCHEMBL20694186 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7030138-B2 | Benzamidine derivatives | SANKYO COMPANY, LIMITED (JP) | 2006-04-18 | — | — | US | disclosed |
| US-20040147555-A1 | Benzamidine derivatives | SANKYO COMPANY, LIMITED (JP) | 2004-07-29 | — | — | US | disclosed |
| EP-1375482-A1 | BENZAMIDINE DERIVATIVE | Sankyo Company, Limited (JP) | 2004-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147555-A1 | Benzamidine derivatives | F9, F7, F2 | SCD 2794/4885MEN1 2403/4885KMT2A 2377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.