SCHEMBL20695599

SCHEMBL20695599

C=C(C)C(=O)NCCCC(OC)=C(OC)OC

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.37
▸ ALDH1A1 P00352 3/20 0.33
▸ EPHX2 P34913 2/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ PLA2G4A P47712 1/20 0.33
▸ KDM4E B2RXH2 2/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ HIF1A Q16665 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ CASP2 P42575 1/20 0.31
▸ ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12332685 0.79 TSHR (0.50) TSHRALDH1A1EPHX2KDM4EMAPK1
SCHEMBL141759 0.78 TSHR (0.55) TSHRALDH1A1EPHX2SMN1; SMN2KDM4E
SCHEMBL18769692 0.77 KDM4E (0.39) ALDH1A1PLA2G4AKDM4EMAPK1HIF1A
SCHEMBL12332686 0.77 EPHX2 (0.49) TSHRALDH1A1EPHX2KDM4EMAPK1
SCHEMBL23269433 0.77 EPHX2 (0.49) TSHRALDH1A1EPHX2KDM4EMAPK1
SCHEMBL632876 0.77 KDM4E (0.46) ALDH1A1KDM4EMAPK1HIF1AADRA1A
SCHEMBL907569 0.77 KDM4E (0.52) ALDH1A1SMN1; SMN2KDM4EMAPK1HIF1A
SCHEMBL7575361 0.76 TSHR (0.33) TSHRALDH1A1EPHX2SMN1; SMN2PLA2G4A
SCHEMBL7113895 0.76 TDP1 (0.39) EPHX2PLA2G4AKDM4EMAPK1HIF1A
SCHEMBL1557480 0.76 ADRA1A (0.53) TSHREPHX2PLA2G4AMAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109563361-B Insulating heat-dissipating coating composition and insulating heat-dissipating article obtained by using same 阿莫善斯有限公司 2023-11-21 — — CN disclosed
EP-3437905-B1 PTC UNIT FOR VEHICLE HEATER, PTC HEATER INCLUDING SAME, AND AIR CONDITIONING DEVICE FOR VEHICLE AMOSENSE CO LTD (KR) 2021-08-18 — — EP disclosed
CN-108883687-B Positive temperature coefficient unit for vehicle heater, positive temperature coefficient heater including the same, and vehicle air conditioner 阿莫善斯有限公司 2021-07-27 — — CN disclosed
CN-109155184-B Coil component 阿莫绿色技术有限公司 2021-03-12 — — CN disclosed
EP-3437905-A1 PTC UNIT FOR VEHICLE HEATER, PTC HEATER INCLUDING SAME, AND AIR CONDITIONING DEVICE FOR VEHICLE Amosense Co., Ltd. (KR) 2019-02-06 — — EP disclosed
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