SCHEMBL141759

SCHEMBL141759

C=C(C)C(=O)NCCCOC

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.55
ALDH1A1 P00352 4/20 0.52
SMN1; SMN2 Q16637 2/20 0.50
RECQL P46063 1/20 0.49
GAA P10253 2/20 0.47
POLB P06746 2/20 0.46
KDM4E B2RXH2 1/20 0.45
LMNA P02545 1/20 0.45
EPHX2 P34913 2/20 0.44
HPGD P15428 3/20 0.43
TDP1 Q9NUW8 1/20 0.42
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
HSD17B10 Q99714 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1454851 0.94 TSHR (0.48) TSHRALDH1A1SMN1; SMN2RECQLGAA
SCHEMBL12643043 0.92 TSHR (0.47) TSHRALDH1A1SMN1; SMN2RECQLGAA
SCHEMBL20613887 0.92 TSHR (0.47) TSHRALDH1A1SMN1; SMN2RECQLGAA
SCHEMBL6932876 0.89 SMN1; SMN2 (0.45) TSHRALDH1A1SMN1; SMN2RECQLGAA
SCHEMBL150973 0.88 TDP1 (0.45) TSHRALDH1A1SMN1; SMN2GAAKDM4E
SCHEMBL24496157 0.86 ALDH1A1 (0.41) TSHRALDH1A1SMN1; SMN2RECQLPOLB
SCHEMBL5528349 0.84 THRB (0.41) TSHRALDH1A1SMN1; SMN2POLBKDM4E
SCHEMBL8949910 0.84 THRB (0.41) TSHRALDH1A1SMN1; SMN2POLBKDM4E
SCHEMBL5413785 0.84 ALDH1A1 (0.40) TSHRALDH1A1SMN1; SMN2POLBKDM4E
SCHEMBL632876 0.83 KDM4E (0.46) ALDH1A1KDM4ETDP1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4076916-B1 WETTABLE SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-06-12 EP claimed
EP-4146461-B1 METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-03-13 EP claimed
EP-3802080-B1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-07-19 EP claimed
US-20200353090-A1 Polymeric prodrugs and subcutaneous and/or intramuscular administration thereof Universite Paris-Saclay (FR) 2020-11-12 US claimed
EP-3710061-A1 POLYMER PRODRUGS AND SUBCUTANEOUS AND/OR INTRAMUSCULAR ADMINISTRATION THEREOF Centre National de la Recherche Scientifique (FR) 2020-09-23 EP claimed
CN-111615405-A Polymeric prodrugs and subcutaneous and/or intramuscular administration thereof 国家科学研究中心 2020-09-01 CN claimed
US-10551345-B2 Poly and copoly(N-vinylamide)s and their use in capillary electrophoresis APPLIED BIOSYSTEMS, LLC (US) 2020-02-04 US claimed
US-20170356877-A1 POLY AND COPOLY(N-VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS APPLIED BIOSYSTEMS, LLC (US) 2017-12-14 US claimed
US-20170258703-A1 IONIC/IONOGENIC COMB COPOLYMER COMPOSITIONS AND PERSONAL CARE PRODUCTS CONTAINING THE SAME EVONIK DEGUSSA GMBH (DE) 2017-09-14 US claimed
US-9671367-B2 Poly and copoly(N-vinylamide)s and their use in capillary electrophoresis APPLIED BIOSYSTEMS, LLC (US) 2017-06-06 US claimed
US-7329694-B2 Ocular lens JOHNSON & JOHNSON VISION CARE, INC. (US) 2008-02-12 US claimed
US-20070211130-A1 Fusible inkjet recording element and related methods of coating and printing EASTMAN KODAK COMPANY 2007-09-13 US claimed
CN-1816573-A (N-vinylamide) polymers and copolymers and their use in capillary electrophoresis APPLERA CORP (US) 2006-08-09 CN claimed
EP-1636279-A1 POLY AND COPOLY (N -VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS Applera Corporation (US) 2006-03-22 EP claimed
US-20050234166-A1 Graft copolymers, their preparation and use in capillary electrophoresis APPLIED BIOSYSTEMS, INC. 2005-10-20 US claimed
EP-1539846-A1 GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS Applera Corporation (US) 2005-06-15 EP claimed
US-20050025741-A1 Copolymers with (meth)acrylamides; improved separation of polynucleotides APPLIED BIOSYSTEMS, LLC 2005-02-03 US claimed
WO-2004104054-A1 POLY AND COPOLY (N-VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS APPLERA CORPORATION (US) 2004-12-02 WO claimed
US-20040191433-A1 Ink-jet recording material MITSUBISHI PAPER MILLS LIMITED (JP) 2004-09-30 US claimed
WO-2004011513-A1 GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS APPLERA CORPORATION (US) 2004-02-05 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200353090-A1 Polymeric prodrugs and subcutaneous and/or intramuscular administration thereof IDE, SI, PYGM TSHR 3972/4885ALDH1A1 385/4885SMN1; SMN2 1038/4885
US-20170258703-A1 IONIC/IONOGENIC COMB COPOLYMER COMPOSITIONS AND PERSONAL CARE PRODUCTS CONTAINING THE SAME C9, CUTA, ZYX TSHR 3364/4885ALDH1A1 2420/4885SMN1; SMN2 2105/4885
US-20050025741-A1 Copolymers with (meth)acrylamides; improved separation of polynucleotides POLI, PCNA, POLL TSHR 4259/4885ALDH1A1 3357/4885SMN1; SMN2 963/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.