Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIK1 | P57059 | 2/20 | 0.34 |
| ▸ | SIK2 | Q9H0K1 | 2/20 | 0.34 |
| ▸ | SIK3 | Q9Y2K2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20698205 | 0.90 | PSEN1 (0.33) | SIK1SIK2SIK3MAPTALDH1A1 | |
| SCHEMBL20698209 | 0.89 | FGFR1 (0.32) | MAPTHPGDPSEN1PSEN2APH1B | |
| SCHEMBL20697990 | 0.84 | FGFR1 (0.39) | MAPTALDH1A1HPGDALOX12SMN1; SMN2 | |
| SCHEMBL20697959 | 0.80 | FGFR1 (0.41) | MAPTALDH1A1HPGDSMN1; SMN2PDE2A | |
| SCHEMBL20698203 | 0.79 | FGFR1 (0.35) | ALDH1A1HPGDFGFR1KDRKCNH2 | |
| SCHEMBL20698012 | 0.79 | FGFR1 (0.37) | MAPTALDH1A1HPGDSMN1; SMN2FGFR1 | |
| SCHEMBL20698301 | 0.78 | SIK1 (0.41) | SIK1SIK2SIK3MAPTALDH1A1 | |
| SCHEMBL20697994 | 0.77 | FGFR1 (0.48) | MAPTALDH1A1HPGDSMN1; SMN2PDE2A | |
| SCHEMBL20698308 | 0.76 | HSD11B1 (0.36) | LMNAPDE2APDE10AFGFR1KCNH2 | |
| SCHEMBL20697928 | 0.75 | HSD11B1 (0.41) | PDE2APDE10AFGFR1KCNH2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019020981-A1 | PYRAZOLE, ISOTHIAZOLE AND ISOXAZOLE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | REDAG CROP PROTECTION LTD. (GB) | 2019-01-31 | — | — | WO | disclosed |