Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20698165 | 0.78 | HSD11B1 (0.44) | HSD11B1FGFR1GRM2MAPK1HTT | |
| SCHEMBL21187500 | 0.78 | HSD11B1 (0.43) | HSD11B1FGFR1GRM2HTTKMT2A | |
| SCHEMBL20698324 | 0.76 | HSD11B1 (0.40) | HSD11B1FGFR1GRM2MAPK1HTT | |
| SCHEMBL20698149 | 0.76 | GRM2 (0.41) | HSD11B1FGFR1GRM2MAPK1HTT | |
| SCHEMBL20697932 | 0.74 | HSD11B1 (0.38) | HSD11B1FGFR1GRM2MAPK1MKNK1 | |
| SCHEMBL20698322 | 0.72 | HSD11B1 (0.40) | HSD11B1FGFR1GRM2MAPK1HTT | |
| SCHEMBL20698323 | 0.72 | HSD11B1 (0.43) | HSD11B1FGFR1GRM2HTTMKNK2 | |
| SCHEMBL20697930 | 0.69 | HSD11B1 (0.41) | HSD11B1PDE2APDE10A | |
| SCHEMBL20697928 | 0.69 | HSD11B1 (0.41) | HSD11B1FGFR1PDE2APDE10A | |
| SCHEMBL21187447 | 0.67 | FGFR1 (0.44) | HSD11B1FGFR1TP53POLBPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019020981-A1 | PYRAZOLE, ISOTHIAZOLE AND ISOXAZOLE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | REDAG CROP PROTECTION LTD. (GB) | 2019-01-31 | — | — | WO | disclosed |