SCHEMBL20698348

SCHEMBL20698348

c1ccc2c(-c3cc(-c4ccc5c6ccccc6c6ccccc6c5c4)cc(-c4cccc5ccccc45)c3)cccc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.47
CA1 P00915 5/20 0.47
CA2 P00918 5/20 0.47
CA9 Q16790 5/20 0.47
MCL1 Q07820 2/20 0.45
ACMSD Q8TDX5 1/20 0.45
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HPRT1 P00492 3/20 0.43
FNTA P49354 1/20 0.42
FNTB P49356 1/20 0.42
ENPP3 O14638 1/20 0.41
ENPP1 P22413 1/20 0.41
KDM4E B2RXH2 2/20 0.40
ALPL P05186 1/20 0.40
GAA P10253 1/20 0.40
PPARG P37231 3/20 0.39
PPARA Q07869 3/20 0.39
CYP2C19 P33261 2/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20124391 0.90 MCL1 (0.53) CA12CA1CA2CA9MCL1
SCHEMBL16407366 0.87 ALDH1A1 (0.47) CA12CA1CA2CA9MCL1
SCHEMBL24837163 0.87 CA12 (0.44) CA12CA1CA2CA9MCL1
SCHEMBL2010178 0.85 CA12 (0.50) CA12CA1CA2CA9MCL1
SCHEMBL29866205 0.85 CA12 (0.50) CA12CA1CA2CA9MCL1
SCHEMBL4927910 0.85 HSD17B1 (0.48) CA12CA1CA2CA9MCL1
SCHEMBL25052541 0.84 MEN1 (0.40) CA12CA1CA2CA9KDM4E
SCHEMBL25052871 0.83 ALOX5 (0.46) CA12CA1CA2CA9MCL1
SCHEMBL16433539 0.81 CA12 (0.49) CA12CA1CA2CA9MCL1
SCHEMBL22259693 0.81 KDM4E (0.43) CA12CA1CA2CA9MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190036043-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-31 US disclosed