SCHEMBL20699863

SCHEMBL20699863

CC(=C(P(=O)(O)O)P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.38
LMNA P02545 1/20 0.35
FDPS P14324 1/20 0.33
MMP2 P08253 1/20 0.32
MMP3 P08254 1/20 0.32
MMP8 P22894 1/20 0.32
TSHR P16473 1/20 0.31
THPO P40225 1/20 0.31
CYP1A2 P05177 1/20 0.31
PKM P14618 1/20 0.31
PTK2B Q14289 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8548508 0.74
SCHEMBL2215479 0.72
SCHEMBL10749742 0.72 FDPS (0.43) FDPS
SCHEMBL8038218 0.71 CA2 (0.38) CA2MMP2MMP3MMP8
SCHEMBL10784240 0.71 CA2 (0.42) CA2FDPSMMP2MMP3MMP8
SCHEMBL777994 0.69
SCHEMBL700464 0.68
Butanedione SCHEMBL222007 0.65 TSHR (0.64) CA2LMNAMMP2MMP3MMP8
SCHEMBL4191596 0.65 CA2 (0.46) CA2LMNAFDPSMMP2MMP3
SCHEMBL444175 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3413934-B1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2021-10-13 EP claimed
CN-109195641-B Improved implant treatment with phosphonic acid compounds 纳米桥接分子股份公司 2021-07-27 CN claimed
US-11000627-B2 Treatment of implants with phosphonic acid compounds NANO BRIDGING MOLECULES SA (CH) 2021-05-11 US claimed
US-20190038802-A1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2019-02-07 US claimed
EP-3413934-B1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2021-10-13 EP disclosed
CN-109195641-B Improved implant treatment with phosphonic acid compounds 纳米桥接分子股份公司 2021-07-27 CN disclosed
US-11000627-B2 Treatment of implants with phosphonic acid compounds NANO BRIDGING MOLECULES SA (CH) 2021-05-11 US disclosed
US-20190038802-A1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2019-02-07 US disclosed