Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.39 |
| ▸ | ACACA | Q13085 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 7/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11028523 | 1.00 | ACACB (0.39) | ACACBACACACHRM2CHRM4CHRM5 | |
| SCHEMBL2072081 | 0.88 | BACE1 (0.37) | ACACBACACACHRM2CHRM4CHRM5 | |
| SCHEMBL1943050 | 0.85 | ACACB (0.45) | ACACBACACABACE1 | |
| SCHEMBL1942308 | 0.85 | ACACB (0.45) | ACACBACACABACE1 | |
| SCHEMBL1941359 | 0.84 | ACACB (0.48) | ACACBACACABACE1DPP4 | |
| SCHEMBL1941357 | 0.84 | ACACB (0.48) | ACACBACACABACE1DPP4 | |
| SCHEMBL561396 | 0.84 | MGLL (0.35) | THRBKMT2AALDH1A1CYP1A2HPGD | |
| SCHEMBL11025895 | 0.82 | ACACB (0.43) | ACACBACACABACE1DPP4SLC6A4 | |
| SCHEMBL2759718 | 0.79 | KMT2A (0.38) | THRBKMT2AALDH1A1HSD17B10HTT | |
| SCHEMBL1943774 | 0.78 | BACE1 (0.37) | ACACBACACABACE1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897803-B2 | Cis-alkoxy-substituted spirocyclic 1H-pyrrolidine-2,4-dione derivatives serving as pesticides | BAYER CROPSCIENCE AG (DE) | 2011-03-01 | — | — | US | disclosed |
| US-20100056598-A1 | CIS-ALKOXY-SUBSTITUTED SPIROCYCLIC 1H-PYRROLIDINE-2,4-DIONE DERIVATIVES SERVING AS PESTICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-03-04 | — | — | US | disclosed |
| US-7638547-B2 | Cis-alkoxy-substituted spirocyclic 1H-pyrrolidine-2,4-dione derivatives serving as pesticides | BAYER CROPSCIENCE AG (DE) | 2009-12-29 | — | — | US | disclosed |
| US-20070032539-A1 | Cis-alkoxy-substituted spirocyclic 1-h-pyrrolidine-2,4-dione derivatives serving as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-02-08 | — | — | US | disclosed |
| EP-1523472-A1 | CIS-ALKOXY-SUBSTITUTED SPIROCYCLIC 1-H-PYRROLIDINE-2,4-DIONE DERIVATIVES SERVING AS PESTICIDES | Bayer CropScience AG (DE) | 2005-04-20 | — | — | EP | disclosed |
| WO-2004007448-A1 | CIS-ALKOXY-SUBSTITUTED SPIROCYCLIC 1-H-PYRROLIDINE-2,4-DIONE DERIVATIVES SERVING AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056598-A1 | CIS-ALKOXY-SUBSTITUTED SPIROCYCLIC 1H-PYRROLIDINE-2,4-DIONE DERIVATIVES SERVING AS PESTICIDES | DDT, CYP4X1, CDY1; CDY1B | ACACB 1977/4885ACACA 2015/4885CHRM2 244/4885 |
| US-20070032539-A1 | Cis-alkoxy-substituted spirocyclic 1-h-pyrrolidine-2,4-dione derivatives serving as pesticides | DDT, CYP4X1, PDHX | ACACB 2047/4885ACACA 2002/4885CHRM2 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.