Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | OTUD7B | Q6GQQ9 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2759719 | 0.90 | TDP2 (0.34) | ALDH1A1KMT2AMEN1POLBHSD17B10 | |
| SCHEMBL2759718 | 0.87 | KMT2A (0.38) | MGLLALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL15182378 | 0.87 | MAPK1 (0.36) | ALDH1A1SMN1; SMN2KMT2ATHRBHSD17B10 | |
| SCHEMBL15182377 | 0.86 | ALOX15 (0.43) | ALDH1A1SMN1; SMN2HSD17B10MAPTUSP2 | |
| SCHEMBL2759720 | 0.86 | ACACB (0.42) | — | |
| SCHEMBL14998141 | 0.85 | OTUD7B (0.32) | OTUD7B | |
| SCHEMBL11028523 | 0.84 | ACACB (0.39) | ALDH1A1SMN1; SMN2KMT2AMEN1THRB | |
| SCHEMBL2070159 | 0.84 | ACACB (0.39) | ALDH1A1SMN1; SMN2KMT2AMEN1THRB | |
| SCHEMBL2759727 | 0.83 | TSHR (0.30) | POLBTSHR | |
| SCHEMBL561086 | 0.82 | OTUD7B (0.32) | OTUD7B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2352375-B1 | HERBICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-03-25 | — | — | EP | disclosed |
| US-8722578-B2 | Spiroheterocyclic pyrrolidinedione herbicidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2014-05-13 | — | — | US | disclosed |
| US-8722578-B2 | Spiroheterocyclic pyrrolidinedione herbicidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2014-05-13 | — | — | US | disclosed |
| EP-2421865-B1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-07-10 | — | — | EP | disclosed |
| EP-2421865-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USED AS PESTICIDES | Syngenta Participations AG (CH) | 2012-02-29 | — | — | EP | disclosed |
| US-20120035201-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-02-09 | — | — | US | disclosed |
| US-20120004105-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2012-01-05 | — | — | US | disclosed |
| US-20120004105-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2012-01-05 | — | — | US | disclosed |
| WO-2010115780-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-10-14 | — | — | WO | disclosed |
| WO-2010052161-A2 | HERBICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004105-A1 | HERBICIDAL COMPOSITIONS | DDT, CAT, HDHD5 | MGLL 637/4885ALDH1A1 262/4885SMN1; SMN2 3310/4885 |
| US-20120035201-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USED AS PESTICIDES | DDT, PKD2, PKD1 | MGLL 4238/4885ALDH1A1 97/4885SMN1; SMN2 2581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.