Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | CASP3 | P42574 | 4/20 | 0.56 |
| ▸ | CASP2 | P42575 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | STK10 | O94804 | 1/20 | 0.48 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalimide SCHEMBL28353587 | 0.87 | GSK3B (0.65) | GSK3BCASP3CASP2CASP7CASP6 | |
| SCHEMBL11422252 | 0.87 | ATM (0.53) | GSK3BALDH1A1CASP3L3MBTL1ATM | |
| Phthalimide SCHEMBL15488735 | 0.86 | GSK3B (0.79) | GSK3BALDH1A1CASP3CASP2CASP7 | |
| Phthalimide SCHEMBL7297919 | 0.84 | GSK3B (0.75) | GSK3BALDH1A1CASP3CASP2CASP7 | |
| Phthalimide SCHEMBL28139797 | 0.83 | GSK3B (0.60) | GSK3BALDH1A1CASP3CASP2CASP7 | |
| Phthalimide SCHEMBL10836528 | 0.83 | PARP1 (0.64) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL3984602 | 0.83 | GSK3B (0.94) | GSK3BALDH1A1CASP3CASP2CASP7 | |
| Phthalimide SCHEMBL30452542 | 0.82 | GSK3B (0.71) | GSK3BALDH1A1CASP3CASP2CASP7 | |
| Phthalimide SCHEMBL4318901 | 0.82 | GSK3B (0.71) | GSK3BALDH1A1CASP3CASP2CASP7 | |
| Phthalimide SCHEMBL11040503 | 0.81 | GSK3B (1.00) | GSK3BALDH1A1CASP3CASP2CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11246956-B2 | Polymer nanofiber scaffolds and uses thereof | CASE WESTERN RESERVE UNIVERSITY (US) | 2022-02-15 | — | — | US | disclosed |
| US-20210015961-A1 | POLYMER NANOFIBER SCAFFOLDS AND USES THEREOF | CASE WESTERN RESERVE UNIVERSITY | 2021-01-21 | — | — | US | disclosed |
| US-10588997-B2 | Polymer nanofiber scaffolds and uses thereof | CASE WESTERN RESERVE UNIVERSITY (US) | 2020-03-17 | — | — | US | disclosed |
| US-20190038796-A1 | POLYMER NANOFIBER SCAFFOLDS AND USES THEREOF | CASE WESTERN RESERVE UNIVERSITY | 2019-02-07 | — | — | US | disclosed |