Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 13/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PPIA | P62937 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2070596 | 0.89 | CYP19A1 (0.64) | CYP19A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL5381129 | 0.86 | CYP19A1 (1.00) | CYP19A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL9524084 | 0.84 | LMNA (0.71) | CYP19A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL13297761 | 0.83 | CYP19A1 (0.77) | CYP19A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL2070257 | 0.82 | PKM (0.78) | MEN1MAPTKMT2ALMNAPKM | |
| SCHEMBL13297754 | 0.82 | CYP19A1 (0.75) | CYP19A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL9524409 | 0.81 | NPC1 (0.64) | CYP19A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL7370166 | 0.81 | CYP19A1 (0.66) | CYP19A1MEN1MAPTKMT2APPIA | |
| SCHEMBL13297757 | 0.80 | CYP19A1 (0.72) | CYP19A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL2069989 | 0.79 | PKM (0.57) | CYP19A1MEN1MAPTKMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906537-B2 | Substituted p-diaminobenzene derivatives | H. LUNDBECK A/S (DK) | 2011-03-15 | — | — | US | disclosed |
| US-20060183791-A1 | Substituted p-diaminobenzene derivatives | H. LUNDBECK A/S (DK) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183791-A1 | Substituted p-diaminobenzene derivatives | ABCB1, UGT2B7, CYP2D6 | CYP19A1 93/4885MEN1 1715/4885MAPT 3488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.