SCHEMBL20705368

SCHEMBL20705368

Cc1cc(Nc2ccc(-c3cc(C)c(-c4ccc(Nc5ccc(-c6ccccc6)c(C)c5)cc4C)cc3C)c(C)c2)ccc1-c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.52
CYP17A1 P05093 1/20 0.46
NPSR1 Q6W5P4 1/20 0.41
HPGD P15428 2/20 0.41
APP P05067 1/20 0.40
LMNA P02545 3/20 0.39
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
ALDH1A1 P00352 5/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 2/20 0.39
KMT2A Q03164 2/20 0.39
AR P10275 1/20 0.39
PLA2G7 Q13093 1/20 0.39
SLC1A3 P43003 1/20 0.38
SLC1A2 P43004 1/20 0.38
SLC1A1 P43005 1/20 0.38
HSD17B10 Q99714 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20705367 0.91 ESR2 (0.50) ESR2CYP17A1NPSR1HPGDAPP
SCHEMBL20705366 0.88 ESR2 (0.47) ESR2CYP17A1NPSR1HPGDAPP
SCHEMBL18493839 0.86 HPGD (0.53) ESR2CYP17A1NPSR1HPGDAPP
SCHEMBL12071483 0.85 GAA (0.47) ESR2CYP17A1HPGDAPPALDH1A1
SCHEMBL29416259 0.84 HPGD (0.58) NPSR1HPGDAPPLMNAALDH1A1
SCHEMBL4639004 0.84 HPGD (0.58) NPSR1HPGDAPPLMNAALDH1A1
SCHEMBL13308526 0.84 HPGD (0.58) NPSR1HPGDAPPLMNAALDH1A1
SCHEMBL4423918 0.83 ESR2 (0.46) ESR2CYP17A1NPSR1HPGDAPP
SCHEMBL15372181 0.82 PLA2G7 (0.43) ESR2CYP17A1NPSR1HPGDAPP
SCHEMBL17735244 0.82 ESR2 (0.49) ESR2CYP17A1LMNAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10199577-B2 Electroactive materials E I DU PONT DE NEMOURS AND COMPANY (US) 2019-02-05 US disclosed