SCHEMBL20706804

SCHEMBL20706804

c1cc(-n2c3ccccc3c3ccccc32)nc(-n2c3ccccc3c3cc(-c4ccc5oc6ccccc6c5c4)ccc32)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.40
ALDH1A1 P00352 3/20 0.40
NPC1 O15118 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 2/20 0.40
HPGD P15428 2/20 0.40
KMT2A Q03164 2/20 0.40
RAB9A P51151 1/20 0.40
PLA2G2A P14555 5/20 0.39
PLA2G4A P47712 5/20 0.39
PLA2G10 O15496 1/20 0.39
CHEK2 O96017 1/20 0.39
CASP3 P42574 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
AHR P35869 2/20 0.36
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15458333 1.00 MAPT (0.40) MAPTALDH1A1NPC1SMN1; SMN2KDM4E
SCHEMBL12455122 0.90 PLA2G2A (0.40) MAPTALDH1A1NPC1SMN1; SMN2KDM4E
SCHEMBL15458313 0.90 NPC1 (0.38) MAPTALDH1A1NPC1SMN1; SMN2KDM4E
SCHEMBL20706680 0.90 CASP3 (0.38) MAPTALDH1A1NPC1SMN1; SMN2KDM4E
SCHEMBL24813199 0.88 PLA2G2A (0.39) MAPTALDH1A1NPC1SMN1; SMN2KDM4E
SCHEMBL25000913 0.88 PLA2G2A (0.44) MAPTALDH1A1NPC1SMN1; SMN2KDM4E
SCHEMBL12175600 0.87 CHEK2 (0.36) MAPTALDH1A1NPC1SMN1; SMN2KDM4E
SCHEMBL17228372 0.87 TUBB4A (0.37) MAPTALDH1A1NPC1SMN1; SMN2KDM4E
SCHEMBL18158874 0.87 KDM4E (0.39) MAPTALDH1A1NPC1SMN1; SMN2KDM4E
SCHEMBL12455103 0.87 MAPT (0.43) MAPTALDH1A1NPC1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10622570-B2 Organic electroluminescent element NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2020-04-14 US disclosed
US-20190088883-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2019-03-21 US disclosed
EP-3439058-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel & Sumikin Chemical Co., Ltd. (JP) 2019-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10622570-B2 Organic electroluminescent element NR2E3, ESR1, NCOR2 MAPT 4309/4885ALDH1A1 2827/4885NPC1 2748/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.