Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR1E | P28566 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28447148 | 0.78 | ALDH1A1 (0.57) | HTR2AHTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL19372678 | 0.77 | MAPT (0.67) | HTR2AADRB1HTR1AADRA2ASLC6A2 | |
| SCHEMBL20619402 | 0.76 | ALDH1A1 (0.64) | HTR2AHTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL27043147 | 0.75 | ALOX15 (0.56) | HTR2AADRB1HTR1AADRA2ASLC6A2 | |
| SCHEMBL4628084 | 0.75 | MEN1 (0.58) | HTR2AADRB1HTR1AADRA2ASLC6A2 | |
| SCHEMBL7855506 | 0.72 | SMN1; SMN2 (0.74) | HTR2AADRB1HTR1AADRA2ASLC6A2 | |
| SCHEMBL26770319 | 0.72 | MAPT (0.55) | MAPTKDM4EPOLBAPAF1RECQL | |
| SCHEMBL12104024 | 0.71 | KDM4E (0.76) | HTR2AADRB1HTR1AADRA2ASLC6A2 | |
| SCHEMBL13662877 | 0.71 | KDM4E (0.76) | HTR2AADRB1HTR1AADRA2ASLC6A2 | |
| SCHEMBL10030545 | 0.71 | KDM4E (0.76) | HTR2AADRB1HTR1AADRA2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3438091-A1 | COMPOUND HAVING ENHANCING ACTIVITY FOR GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ACTIONS | AJINOMOTO CO., INC. (JP) | 2019-02-06 | — | — | EP | disclosed |