Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 4/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | HTR6 | P50406 | 2/20 | 0.57 |
| ▸ | MPO | P05164 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | HTR1D | P28221 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20619402 | 0.90 | ALDH1A1 (0.64) | ALDH1A1MAPTCYP1A2MEN1KMT2A | |
| SCHEMBL22302371 | 0.85 | MAPT (0.59) | ALDH1A1MAPTCYP1A2MEN1KMT2A | |
| SCHEMBL29611317 | 0.83 | MAPT (0.66) | ALDH1A1MAPTCYP1A2MEN1KMT2A | |
| SCHEMBL1250315 | 0.83 | MAPT (0.66) | ALDH1A1MAPTCYP1A2MEN1KMT2A | |
| SCHEMBL4628084 | 0.83 | MEN1 (0.58) | ALDH1A1MAPTCYP1A2MEN1KMT2A | |
| SCHEMBL24630467 | 0.81 | HTR2A (0.59) | ALDH1A1CYP1A2MEN1KMT2ALMNA | |
| SCHEMBL4985934 | 0.80 | HTR2A (0.77) | ALDH1A1MAPTCYP1A2MEN1KMT2A | |
| SCHEMBL12712632 | 0.80 | MEN1 (0.74) | ALDH1A1CYP1A2MEN1KMT2ALMNA | |
| SCHEMBL12691109 | 0.79 | MEN1 (0.59) | ALDH1A1MAPTCYP1A2MEN1KMT2A | |
| SCHEMBL20707168 | 0.78 | HTR2A (0.51) | ALDH1A1MAPTCYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484436-B | Method for introducing isopentene group into C3 position of indole | 中国科学院大连化学物理研究所 | 2022-06-07 | — | — | CN | disclosed |
| CN-111484436-A | Method for introducing isopentenyl group to C3 position of indole | 中国科学院大连化学物理研究所 | 2020-08-04 | — | — | CN | disclosed |