Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17315810 | 0.86 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL14932582 | 0.75 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL17315789 | 0.72 | KDM4E (0.38) | L3MBTL1ALDH1A1KMT2AAGBL2POLB | |
| SCHEMBL17315815 | 0.72 | KDM4E (0.38) | L3MBTL1ALDH1A1HPGDPOLBGAA | |
| SCHEMBL19371277 | 0.71 | ALDH1A1 (0.52) | L3MBTL1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL17315802 | 0.70 | S1PR1 (0.41) | L3MBTL1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL17622561 | 0.70 | KDM4E (0.39) | L3MBTL1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL28704182 | 0.70 | ALDH1A1 (0.54) | L3MBTL1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL17315809 | 0.69 | AGBL2 (0.44) | ALDH1A1HPGDMEN1KMT2AAGBL2 | |
| SCHEMBL30747027 | 0.69 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3194403-B1 | PYRROLOPYRIMIDINE DERIVATIVES AS NR2B NMDA RECEPTOR ANTAGONISTS | RUGEN HOLDINGS CAYMAN LTD (KY) | 2019-02-06 | — | — | EP | disclosed |